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JOURNAL OF INTEGRATIVE NUTRITION

CLINICAL EDUCATION FACT SHEET

Understanding Multiple Sclerosis and Its Connection to Stress

Hollywood, JB

FIRST PUBLISHED

2025-02-01

Article:

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ABSTRACT

Background: Multiple Sclerosis (MS) is a chronic autoimmune disease that can be onset due to excess stress.

Purpose: The aim was to briefly investigate MS in relation to stress associations and provide a guide for practitioners that will direct their course of action in the event a client presented with this condition.

Results: A nutrition protocol was developed for alternative treatment options.

Conclusion: Based on stress’s effect on the innate immune system, vitamin B1, vitamin B3, vitamin B6, vitamin B9 (folate), vitamin B12, and CO₂-rich foods, may serve as foundational starting points for developing MS nutrition protocols.

COI STATEMENT

The authors declare no competing financial interests.

REFERENCES

1. Hollywood JB. Management of Trauma-Induced Multiple Sclerosis with Paleo Diet and Integrative Therapies: A Case Report. Integr Med (Encinitas). 2024;23(1):32-37.


2. Khosravi-Largani M, Pourvali-Talatappeh P, Rousta AM, et al. A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis. eNeurologicalSci. 2018;10:37-44. Published 2018 Jan 28. doi:10.1016/j.ensci.2018.01.007


3. Sharif K, Watad A, Coplan L, et al. The role of stress in the mosaic of autoimmunity: An overlooked association. Autoimmun Rev. 2018;17(10):967-983. doi:10.1016/j.autrev.2018.04.005


4. Bourre JM. Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. J Nutr Health Aging. 2006;10(5):377-385. https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=d8b286c06f207463c7756a773fd62ce73092a226

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