JOURNAL OF INTEGRATIVE NUTRITION
CLINICAL EDUCATION FACT SHEET
Nutrition, Diet Protocol, and Nutrigenomic Considerations for Mannose-Binding Lectin (MBL) Deficiency
Hollywood, JB
FIRST PUBLISHED
February 1, 2025
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ABSTRACT
Mannose-binding lectin (MBL) deficiency is a condition that affects an individual’s immune system causing low levels or deficit of the MBL protein in their blood affecting the innate immune system. The aim was to briefly investigate MBL deficit gene associations and provide a guide for practitioners that will direct their course of action in the event a client presented with this condition. A nutrition protocol was developed for alternative treatment options. Based on MBL's effect on the innate immune system, polyphenols, vitamin C, vitamin D, zinc, cruciferous vegetables, microbial foods, low-glycemic foods, and adequate hydration may serve as foundational starting points for developing nutrition protocols.
COI STATEMENT
The authors declare no competing financial interests.
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